Uncover the Ability of YOUR Genes
The Link Between Genes and Disease
Many diseases have their roots in our genes. Genes through the proteins they encode, buy cialis doctor determine how efficiently we process foods, sickness how effectively we detoxify poisons and how vigorously we respond to infections. More than 4, viagra 000 diseases are thought to stem for mutated genes inherited from one’s mother and/or father. When a gene contains a mutation, the protein encoded by that gene will be abnormal. Some protein changes are insignificant, while other disabling. Common disorders such as heart disease, obesity and depression arise from a complex interplay among multiple genes and exposure to factors in the environment.
Great advances recently made in human genetics allow for the customization of preventive healthcare advice to suit the genetic profile of an individual. nutraMetrix fashioned the Gene SNP DNA screening analysis to be a power tool that can help you make the dietary and lifestyle changes best suited for your particular needs.By using the Gene SNP Analysis, we can assist you in making an educated decision on the use of, form, and even amounts of targeted nutrients. (Gene SNP DNA Analysis is not available in New York or outside the United States, including Canada.)
Heart health depends on a balance of environmental, dietary, and genetic factors. The Gene SNP analysis screens for genes that affect a variety of factors linked with heart health, including the metabolism of cholesterol, leptin, Adiponectin, antioxidant activity, and increase risk for homocysteinemia. While some people have genetic variations that have an impact on the way their bodies use B vitamins or successfully methylate proteins, others have issues with leptin and insulin sensitivity.
Sufficient or efficient methylation pathways are intrinsic to overall health and protection from the environment. Methylation support is important in heart health as well as fertility and mental health.
Toxin substances can cause tissue irritation or produce a wide range of harmful effects: including inflammation, excess cytokine production, and impaired immune responses. Because toxin accumulation alters the body’s metabolism and may cause enzyme dysfunction, we see concomitant nutritional deficiencies and hormonal imbalance. All of which may contribute to physiological decline.
Some toxins can accumulate in the body faster than they can be eliminated or neutralized. Certain genetic variations are implicated in sluggish enzymes preventing sufficient detoxification and limit our body’s ability to neutralize free radicals and toxins. These antioxidants affect how well our bodies neutralize free radicals that result in reduced oxidative stress (a destructive condition associated with aging and many chronic diseases). In addition, our bodies produce their own antioxidants, which are encoded by our genes.
Inflammation is the body’s response to injury, infection, or foreign proteins. Inflammation is characterized by pain, redness, heat, swelling, and altered function of affected tissue. Although the ability to mount an inflammatory response is essential for survival, the ability to control inflammation is also necessary for health.
Some gene variations produce altered proteins that may hinder inflammatory processes from shutting down when needed. Excess and chronic inflammation is associated with many diseases today. The Gene SNP analysis provides insights into a person’s inflammatory control mechanisms. Evidence shows nutrients, such as omega-3 fatty acids, can have a beneficial effect on maintaining a healthy inflammatory response, by altering inflammatory mediator production.
(IR) is a physiological condition in which cells fail to respond to the normal actions of the hormone insulin. The body produces insulin, but the cells in the body become resistant to insulin and are unable to use it as effectively, leading to hyperglycemia. Multiple genetic variations dictate receptor sensitivity and activity including reducing subsequent increase in the production of insulin due to free fatty acids and contributing to hyper-insulinemiaWilcox G. Insulin and Insulin Resistance. Clinical Biochemist Reviews. 2005; 26(2):19-39..Left undetected can contribute to a diagnosis of Type 2 Diabetes or latent autoimmune diabetes of adults. Free fatty acids play an important role in regulating insulin secretion response and sensitivity. Acute elevated free fatty acids increased insulin secretion and glucose-stimulated insulin secretion.
Mental and Emotional
Depressed people can feel sad, anxious, empty, hopeless, helpless, and much more. They may lose interest in activities that were once pleasurable, experience loss of appetite or overeating, have problems concentrating, remembering details or making decisions, and may contemplate suicide. Depression is a feature of some psychiatric syndromes such as major depressive disorder but it may also be a normal reaction to certain life events. Recent identification of obesity predisposing genes that are highly expressed in the brain raises the possibility of their genetic contribution to depression. Multiple variations contribute to polygenic obesity and may contribute to depression.
Obesity is one of the most important health challenges faced by patients and is increasingly affecting adolescents and children. Obesity is also a considerable risk factor for the development of numerous other chronic diseases, such as insulin resistance, type 2 diabetes, heart disease and nonalcoholic fatty liver disease. The epidemic proportions of obesity and its numerous comorbidities are bringing into focus the highly complex and metabolically active adipose tissue. Adipose tissue is increasingly being considered as a functional endocrine organ.Since its first report from a GWAS of obesity, an increasing number of markers have been shown to be associated with BMI, fat distribution, and metabolic syndrome.